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Refrigeration is optional , only helpful in extreme heat

A2: The results may vary depending on individual factors such as metabolism and lifestyle

[DOI] [PMC free article] [PubMed] [Google Scholar] 59.de Nies L., Galata V., Martin-Gallausiaux C., Despotovic M., Busi S.B., Snoeck C.J., Delacour L., Budagavi D.P., Laczny C.C., Habier J., et al

doi: 10.1038/s41467-018-05470-4 226 ChyanYJPoeggelerBOmarRAChainDGFrangioneBGhisoJet al

There were insignificant changes of some inflammatory markers in some studies, which might be related with short trial duration and inadequate weight loss (6)