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13 C-NMR (100 MHz, CDCl 3 ) ppm = 171.1, 164.4, 150.5, 142.8, 134.9, 134.4, 132.9, 129.0, 128.9, 128.4, 128.0, 127.9, 127.0,0 124.0, 123.9, 123.4, 119.9, 109.3, 50.9, 46.5, 21.9, 20.7, 11.4, 11.1

Science 334 , 105108 (2011)

Vandeputte et al., 2016)

(Menopause definitely counts as a time of stress!) Epidemiological studies have shown higher vitamin C plasma concentrations in women, suggesting that women may need more of it than men , and low concentrations in both sexes have been associated with symptoms of aging, including cognitive decline

In addition, enhanced sampling was carried out by FEL to analyze trajectories (FEL coordinates at different time intervals are provided in Supplementary Table 11)

High-dose administration of either pro-inflammatory agents [e.g., Lipopolysaccharide (LPS)] or anti-inflammatory drugs (e.g., ibuprofen) impairs neuroplasticity, whereas low-dose treatments produce minimal adverse effects (Golia et al., 2019)