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In fact, overproduction of ROS may lead to a decrease in respiratory enzyme activities and mitochondrial membrane potential (MMP) 11,12,13

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Physiological effect IGF-1 is also produced locally in all bodily tissues [6]

Additionally, serotonin-norepinephrine reuptake inhibitors (SNRIs) such as duloxetine, venlafaxine, and milnacipran are employed to provide pain relief and to help manage depression, which is often a coexisting condition in patients with long COVID

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