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The mechanistic consequence is that GHRP-6 activates the full biological program that ghrelin controls not just GH secretion, but somatostatin suppression, appetite signaling via NPY/AgRP pathways, gastric motility, and elements of the reward circuitry

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In both instances, we observed an increase in senescence on cisplatin treatment and a reduction in the cisplatin + RSL3 sections (Fig