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The blockade of proinflammatory cytokine receptors results in restored GABA function and the attenuation of mechanical and cold hypersensitivity [176]

Mater Lett 24, 133138

Also, in vitro studies indicate that the responsiveness of pro-B cells to IL-7 is compromised in aged individuals [355], and IL-7 release from stromal cells in the bone marrow also declines with age [356], leading to reduced pro B-cell proliferation