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This sustained WBC elevation can reflect the activity or severity of the underlying disease and sometimes guides treatment decisions

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2.2 Heat stress and reproduction One of the major physiological effects of heat stress in cows is reduced fertility, as it significantly impairs their ability to establish and maintain pregnancy (Jordan, 2003)

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Genetic predisposition First-degree relatives have a higher likelihood of developing IC/PBS compared to the general population, indicating that the occurrence of the disease may have a zygotic link, whether monozygotic (identical twins) or dizygotic (fraternal twins) (Warren et al., 2004)

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