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The strongest effects of stress are seen in those with pre-existing cardiovascular disease

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Prior to the specification of the sclerotome, the somites are derived from the paraxial mesoderm through the inhibition of bone morphogenetic protein (BMP) signaling in the lateral plate mesoderm by follistatin, an activin-binding protein, working in tandem with Noggin (Stafford et al., 2014)

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NO pathway research can include: NOS activity eNOS signalling NO release markers vascular relaxation response oxidative stress balance endothelial cell function angiogenesis response This makes the NO system a useful bridge between gastrointestinal, vascular and soft tissue studies