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Common maintenance approaches include staying at the dose where you stabilized (often 1.0 to 1.7 mg), reducing by one dose level from your peak (e.g., from 2.4 mg to 1.7 mg), or finding the minimum dose that prevents weight regain while minimizing side effects

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Its chosen based on what each patient needs

In older age, vitamin B12 absorption tends to be less efficient due to a range of health issues, including gastritis stomach lining inflammation and thinning but also because of decreased production of stomach secretions (EFSA, 2015

For instance, when excluding both supplements and medications, those with a deficient-low B 12 status had a significantly increased risk of incident depressive symptoms (OR 165 (95 % CI 107, 254)

Publisher Responsibility: The publisher of this article has made every effort to ensure accuracy at the time of publication based on preclinical research, company-provided information, and publicly available data