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A drug-sensitivity analysis showed that the cellular survival rate of VRK2-KO cells was significantly lower than that of VRK2-WT cells when treated with APR-017 or LCS3 (Fig

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302 Phase IIa and IIb clinical trials investigating the combination of the mTORC1 inhibitors RTB101 and RAD001 revealed that this regimen could reduce immunosenescence and enhance the response to influenza vaccination