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10.1016/j.celrep.2020.107674 [DOI] [PubMed] [Google Scholar] 256.De Rudder C, Garcia-Timermans C, De Boeck I, Lebeer S, Van de Wiele T, Calatayud Arroyo M

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This study also identified decreased concentrations of complexes I, III, IV, and V and weakened activities of complexes I and IV [79]

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These repetitive redox cycles allow for the regeneration of the pools and the maintenance of the cellular redox buffers in a highly reduced state in most cellular compartments under unstressed conditions

Current research on ferroptosis in MDS is mostly at the in vitro and animal model stages and has not yet expanded to clinical studies in patients