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In a randomized placebo-controlled trial with 94 healthy participants, those given 600 mg of an extract containing components from the same two sage species had better scores on some memory tests administered two and four hours after treatment compared with those given placebo

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This is because it is simple to use and because it is administered directly into the systemic circulation, avoiding the first hepatic passage and the potential appearance of unwanted metabolites

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Zhang, T., Wei, H., Deng, J., Zheng, F., & Zhan, C.-G