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[DOI] [PMC free article] [PubMed] [Google Scholar] 193.Kang R., Zeng L., Zhu S., Xie Y., Liu J., Wen Q., Cao L., Xie M., Ran Q., Kroemer G., et al

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People carrying reduced-activity variants tend to clear food-derived histamine more slowly, which is why high-histamine meals aged cheese, cured meats, fermented foods, wine can trigger reactions

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Specifically, it represents a modified version of amino acids 176-191 from the growth hormone molecule, the segment researchers identified as responsible for growth hormones lipolytic (fat-breaking) effects