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doi: 10.3390/nu14010137 48 MarnLMigulezEMVillarCJLombF

Recent animal studies have shown that strains such as Lactobacillus plantarum and Lactobacillus rhamnosus GG can alleviate alcohol-associated hepatic steatosis, liver injury, and gut microbiota dysbiosis [194, 260, 261]

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Typical indications include: severe traumatic brain lesions with markedly impaired level of consciousness (Glasgow Coma Scale 8 or lower ), acute hydrocephalus caused by intraventricular blood , massive intraventricular hemorrhage with impaired or obstructed cerebrospinal fluid circulation , the need for deep sedation and mechanical ventilation in patients with traumatic brain lesions on CT that demonstrate extensive mass effect or are at high risk of secondary intracranial pressure elevation