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Identifying the specific gene-expression changes responsible for this persistence is an open research direction

Pathways of neurosteroid biosynthesis in cell lines from human brain: regulation of dehydroepiandrosterone formation by oxidative stress and beta-amyloid peptide

Tyrosine metabolism and immune cell differentiation Tyrosine metabolites, such as catecholamines (including epinephrine and norepinephrine), play an important role in the differentiation and function of immune cells

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On DIV12 the neurons were fixed (4% paraformaldehyde, 3% sucrose, 60 raM PIPES, 25 mM HEPES, 5 mM EGTA, 1 niM MgCl 2 , pH 7.4) for 20 min at room temperature and mounted

However, the specific approach to combining the two modalities affected the performances (Table 2)