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Dysfunctional lung anatomy and small airways degeneration in COPD

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Its effect relies on blocking the function of the vitamin K epoxide reductase complex (VKOR) in the liver, then inhibiting the K-dependent coagulation factors II, VII, IX, and X [64]

Interestingly, manipulating acetaldehyde concentrations in the brain does not affect alcohol intake in animal models that have consumed alcohol chronically for one to two months, suggesting that alternative mechanisms sustain long-term alcohol intake (143, 144)

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Am J Ther 13(3):205210 Choi S et al (2002) Angiogenic activity of -sitosterol in the ischaemia/reperfusion-damaged brain of Mongolian gerbil