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Int J Biochem Cell Biol 2009;41:1304-14

AAV-PHP.B-mediated global-scale expression in the mouse nervous system enables GBA1 gene therapy for wide protection from synucleinopathy

Mercaptoacetic acid was dimerized in the presence of trifluoroacetic acid and acetone and then reduced with lithium aluminum hydride into the linker 2,2-(propane-2,2-diylbis(sulfanediyl))diacetic acid (synthetic strategy: Supplementary Fig

This suggests the MTHFR C677T mutation is a genetic risk factor of IS, and primary and secondary prevention should be initiated in a timely manner in population with this mutation

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Body aches are common, and the cause remains unclear, though it may involve immune dysfunction or viral triggers