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Niacin can also have an antagonistic effect on gout medications: it elevates uric acid levels, which may counteract drugs like allopurinol or pegloticase that are meant to lower uric acid

We ask that patients enter the office unaccompanied

Am.J Clin.Nutr 1994;60(6):930-935

Should not be used for the treatment of Vitamin B12 deficiency without confirming the diagnosis through proper blood tests, as the treatment may mask other serious health conditions