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Ginger was shown to significantly decrease proinflammatory mediator levels, including TXB2, NO, IL-1, and PGE2, in LPS-activated macrophages of the experimental mouse model of intermittent cold stress-induced fibromyalgia syndrome (FMS)

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Clin Biochem 2009;42:10821090

The role of sex hormones

Consistent with the observation that GSNO in a great excess of CoA reduces PDHC inhibition, we also found that although a low concentration of SNO-CoA in the presence of NADH can cause substantial inhibition of PDHC, adding a larger amount of the NO donor PAPA NONOate on top made the overall inhibition weaker (Fig

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