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Each developmental phase has increasingly focused on adapting to complex biological environments, achieving superior targeting performance, and enhancing therapeutic efficacy

This suppression is reversible but can persist for 24 weeks after discontinuation depending on dose and duration

Nrf2 deficiency exacerbated CLP-induced pulmonary injury and inflammation through autophagy- and NF-B/PPAR-mediated macrophage polarization

Ratter, J

During the pathogenesis of neurodegenerative diseases, activated microglia-mediated neuroinflammation plays a crucial role [82], and targeting mitophagy is an effective approach for inhibiting the activation of microglia