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The synergy is multiplicative, not additive

The REL in the peel was not significantly influenced by aqueous ozonation when the fruit were cold stored for 21 d followed by ambient ripening for 6 d, whereas the highest REL ( P 0.05) was recorded in control fruit when cold stored for 28 d and ripened at ambient conditions for 6 d (Table 2)

However, urine-organic acid analysis showed a high 5-oxoproline level [1,100 (normal range: 010.0)], suggestive of a defect in GSH metabolism

Blood, 2011

placebo for skin lightening." J Pakistan Assoc Dermatol

[DOI] [PMC free article] [PubMed] [Google Scholar] 46.Wang K., Jiang Y., Wang W., Ma J., Chen M