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However, validated medical treatments (UVB phototherapy, topical corticosteroids, calcineurin inhibitors, JAK inhibitors such as ruxolitinib) can enable partial or complete repigmentation in some patients

All mice were approved by the Laboratory Animal Welfare Ethics committee at Harbin Institute of Technology (Approval No: IACUC- 2024138) and conducted in accordance with the Guide for Care and Use of Laboratory Animals and the institutional ethical guidelines for animal experiments

12 weeks: 84 shots needed

Woolston et al

Besides CoQ and VK, which act as RTAs to inhibit ferroptosis, reduced forms of vitamin E, vitamin A, and tetrahydrobiopterin (BH4) are also included

LTRPC2 Ca 2+ -permeable channel activated by changes in redox status confers susceptibility to cell death