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Although adult rodent models remain invaluable in this regard, there is also a clear need for juvenile rodent models and humanized, or human, model systems that will facilitate clinical translation

Masoumi M., Mehrabzadeh M., Mahmoudzehi S., et al., Role of Glucose Metabolism in Aggressive Phenotype of FibroblastLike Synoviocytes: Latest Evidence and Therapeutic Approaches in Rheumatoid Arthritis, International Immunopharmacology 89, no

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Phcog Rev 5:19 Kumar P, Duhan M, Kadyan K, Sindhu J, Kumar S, Sharma H (2017) Synthesis of novel inhibitors of -amylase based on the thiazolidine-4-one skeleton containing a pyrazole moiety and their configurational studies

For instance, astrocytic LDHA downregulation in Alzheimers disease may not only impair energy supply but also directly suppress synaptic plasticity genes via epigenetic modifications (e.g., H3K18 lactylation)(Yao et al., 2023)

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