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Duarte [email protected] This article was submitted to Brain Imaging Methods, a section of the journal Frontiers in Neuroscience Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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Research has shown that the area under the concentration-time curve (AUC) correlates linearly with the administered dose, and no significant differences in the pharmacokinetics of AS-IV have been observed between rats and Beagle dogs (Zhang et al., 2007)

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