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286 Compared with those in the control group, the hepatic CTGF levels and severity of liver fibrosis were lower in the hepatocyte-specific p53-deficient group, whereas the extent of hepatocyte apoptosis was similar

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In response to immunotherapy, CD8 2 T cells release IFN-, which targets system Xc , curtails cystine uptake, and thereby sensitizes tumor cells to ferroptosis (207)

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The authors performed a 6-minute walk test (6-MWT), measured a frailty phenotype, and performed multiple biochemical tests

In a small, exploratory, randomized, placebo-controlled trial that included 27 cancer patients being treated with a chemotherapy agent known to cause ototoxicity, those given oral D-methionine (100 mg per kg of bodyweight) along with chemotherapy were protected from drug-induced hearing loss