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We showed that the yeast-locked mutant strains efg1 / cph1 and eed1 can cause host cytotoxicity in vitro when albumin is present

Cellular senescence in aging primates

The inclusion of a hexahistidine-tag in sdAbs (and other recombinant proteins) initially serves purification purposes (57, 58), however, it also offers the advantage of easy radiolabeling with 99m Tc through tricarbonyl chemistry ( 99m Tc proves to be an ideal radioisotope for the design of bimodal sdAb tracers given its wide availability via 99 Mo/ 99m Tc-generators, its half-life aligning well with the blood half-life of sdAbs (49), its relatively low radiation energy profile enhancing the safety for both patients and personnel, and its routine use for gamma-probing in the operating theatre, meaning all hardware, protocols and experience is available

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A 2003 study by Staresinic, Sebecic, Patrlj, and colleagues in Journal of Orthopaedic Research used a rat Achilles tendon transection model with BPC-157 administered intraperitoneally once daily at 10 g/kg, 10 ng/kg, or 10 pg/kg and reported improved load-to-failure, Young's modulus of elasticity, and Achilles functional index scores, reduced tendon defect size by day 14, and increased tendocyte outgrowth in vitro with specific numerical effect sizes and p-values not reported in the abstract

To confirm that the difference in the peak shift was mainly due to phase transition instead of the effect of temperature, DLPC liposomes were immobilized at 25 C and 50 C