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10.1021/acsearthspacechem.8b00102 13 DickinsonD

Cheng K Co-Delivery of IKBKE siRNA and Cabazitaxel by Hybrid Nanocomplex Inhibits Invasiveness and Growth of Triple-Negative Breast Cancer

Bonnet C, Kaltimbacher V, Ellouze S, Augustin S, Benit P, Forster V, et al

Side Effects & Safety Injection site reactions -- mild redness, minor irritation (standard for SC peptides) Drowsiness -- some users report increased sleepiness with evening dosing (likely melatonin-related) Vivid dreams -- frequently reported, consistent with enhanced melatonin Mild headache -- occasional, typically transient Short course duration limits cumulative exposure Telomerase activation concern -- theoretical cancer risk, though no evidence in available studies Cancer history -- community protocols and researchers frequently note that individuals with active cancer or cancer history are typically excluded from documented protocols