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Therefore, if the pH of sachets is near pH 10, nicotine can be transformed into almost 99% freebase nicotine, which is more bioavailable and can cross the oral mucosa faster and more rapidly, increasing the amount of nicotine in the bloodstream [65]

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Whether it be former smokers or people who never consider themselves to be a smoker, there seems to be a steady trend of people who engage in smoking occasionally often in social settings such as when out on the weekends or while drinking

4.3 ERP data analysis In the ERP (Event-Related Potential) analysis of this study, the EEG (electroencephalogram) data were segmented from 200 milliseconds prior to the stimulus presentation to 800 milliseconds post-stimulus