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Introduction Introduction Thalassemia is an inherited hemoglobin disorder characterized by ineffective erythropoiesis, chronic hemolysis, and the need for regular blood transfusions in severe cases [1,2]

10.1007/s00441-016-2464-0 60 TaoY.AuperinA.SireC.MartinM.SaliouM

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That changes the entire pharmacokinetic profile and makes it a fundamentally more tractable research tool for studies requiring sustained IGF1R activation

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Cells, particularly neurons, have developed sophisticated systems to regulate iron homeostasis through absorption, storage, and output, involving transferrin (TF)-transferrin receptor (TfR), ferritin (FT), and ferroportin (FPN) (Figure 1B