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This regulation highlights the significance of Nrf2 inhibition in triggering ferroptosis ( 3.2 The involvement of ferroptosis in renal fibrosis The kidney is a crucial organ involved in iron filtration and reabsorption, thereby regulating iron metabolism

Being an essential signal molecules of human body, SCFAs are also involved in the regulation of metabolism by gut microbiota, such as cholesterol biosynthesis, glucose homeostasis and insulin sensitivity (Lee et al., 2020)

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