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A B12 deficiency can also be the result of: Cobalamin malabsorption (intestinal diseases, gastric/intestinal resection, atrophic gastritis, pancreatic insufficiency) Low gastric intrinsic factor (dietary intake deficits are less common) Drug interactions

(33896531) This is more likely to be due to acute encephalitis (see NORSE and FIRES in the section below)

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This allows the medication to disperse slightly and reduces the chance of it leaking back out through the needle track

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Radiotherapy affects regional vascular structures, leading to increased vascular fragility in the periorbital area