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3336 Mitochondrial dysfunction manifests in multiple aspects, including mutations and deletions in mitochondrial DNA (mtDNA), disrupted calcium homeostasis, depolarization of the mitochondrial membrane, abnormal fusion and fission processes, impaired mitochondrial biogenesis, and oxidative stress

Deprescribing inappropriate or unnecessary medications impacts clinical outcomessuch as reduction in hospitalizations, ED visits, falls and overall healthcare costsmitigates ADEs, and improves quality of life

Several studies have explored the therapeutic application of both native and mimetic forms of SOD to counteract this oxidative burden (Table 1)

Every treatment plan is built around your biology, your goals, and your life

During the last several years, there have been significant discoveries regarding the role of BAs in immunity and inflammation

This is why trial protocols pair the drug with a calorie deficit plus physical activity, and why resistance training and protein intake come up in every clinical discussion of these medications