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The possible reasons are as follows: (1) the deficiency was not diagnosed properly on the basis of blood B 12 statusthere was no real deficiency in the tissues

As transcriptional factors, the HIF family has a vital role in transcriptional response to hypoxic stress by regulating different target genes

Factors such as age, sex, baseline fitness level, genetic polymorphisms, and even vitamin D status may modulate the degree to which these growth factors are upregulated

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Studies have shown that the sustained occurrence of mild TBI can increase the risk of Parkinsons disease in patients over 55 years old in 57 years (Gardner et al., 2015), which may also be related to excessive iron deposition after TBI