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Common symptoms include: Constant fatigue Weakness Pale skin Tingling or numbness Difficulty walking Memory problems Poor concentration Mood changes Mouth ulcers Breathlessness Loss of appetite Severe deficiency requires prompt medical evaluation

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In fact, some trials observed slight improvements in metabolic markers, likely secondary to fat loss rather than direct peptide effects

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We also list number of cases and hazard ratio of NNMT expression in the multivariate analyses