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a higher proportion of patients with low baseline ALP leads to higher response rates in both investigational and placebo groups

As a result, we begin to lose collagen, and our skin loses its suppleness and strength

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Deletion of PRKAA triggers mitochondrial fission by inhibiting the autophagy-dependent degradation of DNM1L

Key results, proposed mechanisms, and limitations across relevant animal, observational, and clinical studies are summarized in Table 3