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Potential mechanisms of uremic muscle wasting and the protective role of the mitochondria-targeted antioxidant Mito-TEMPO

(4) increased hepatic and renal urea cycle intermediates suggesting hypercatabolism and upregulation of the urea cycle independent of impaired renal clearance of nitrogenous waste

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This research showed that GSH supplementation of amino acids (including L-glycine) and micronutrients (including vitamin C, vitamin E, and magnesium), as well as specific dietary patterns (vegetarian, the Mediterranean diet, and the DASH diet) had the potential to raise glutathione concentrations, which in turn slowed the rate of tissue deterioration

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(2013) 2:e25474