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The potential role of the ubiquitin-proteasome system (UPS) in the regulation of glutamine metabolism in tumor cells remains to be fully elucidated

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IFN also induces an increase in barrier permeability through the reduction of ZO-1 and occludin expression in an adenosine monophosphate-activated protein kinase (AMPK)-dependent pathway, irrespective of the cellular energy levels 62

For instance, the genetically engineered probiotic strain Escherichia coli Nissle 1917 colonizes tumor sites and continuously converts ammonia metabolites into L-arginine

Uffelmann, E

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