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Although the precise etiology of PD remains unclear, factors such as oxidative stress, lipid metabolism dysregulation, metal ion metabolic disorders, mitochondrial dysfunction, and glial cell activation are known to contribute to the progression of PD, suggesting that ferroptosis plays a significant role in its pathogenesis (Wang ZL

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(B) The cellular GSH level was measured at 6 hour post-incubation

In the TME, MDSCs can survive in a high ROS environment because of their high expression of NRF2

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Activity-dependent release of endogenous brain-derived neurotrophic factor from primary sensory neurons detected by ELISA in situ