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Bruising is okay

Current treatment guidelines for CLE, using the BAD guidelines as a model, emphasize a stepwise approach beginning with general management strategies such as photoprotection, smoking cessation, vitamin D supplementation, evaluation for drug-induced CLE (DI-CLE) (especially in SCLE) and screening for systemic lupus erythematosus (SLE), often in collaboration with rheumatology

& Lushchak, V

This is why the 3-month cycle framework exists and why a single injection produces minimal results compared to a structured protocol

Ali noted that anti-inflammatory medications such as ibuprofen can also be beneficial

The Human Trial Void: The most critical limitation is the profound lack of large-scale, robust, placebo-controlled human clinical trials to confirm the safety and efficacy of these peptides