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Vzquez-Meza H, Vilchis-Landeros MM, Vzquez-Carrada M, Uribe-Ramrez D, Matuz-Mares D

doi: 10.1038/s41598-022-11236-2 Summary Keywords metformin, rectal cancer, colorectal, radiosensitiser, energy metabolism, radioresistance Citation Buckley CE, OBrien RM, Nugent TS, Donlon NE, OConnell F, Reynolds JV, Hafeez A, ORordin DS, Hannon RA, Neary P, Kalbassi R, Mehigan BJ, McCormick PH, Dunne C, Kelly ME, Larkin JO, OSullivan J and Lynam-Lennon N (2023) Metformin is a metabolic modulator and radiosensitiser in rectal cancer

Given the prior benefits we observed for NAC in our Seahorse assays, we tested if NAC could restore intracellular GSH, which it did (Fig

3.2 Metals Humans also require various minerals and trace elements to sustain vital life processes

However, it has the limitation of not simulating clinical chronic wound bacterial biofilms