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At follow-up, WC (91.712.5 vs

Munc18-1 null neurons expressing Cre-EGFP plus either Munc18-1 wt, Munc18-1 Q301R, or Munc18-1 Q301D using lentiviral vectors were all viable, unlike uninfected munc18-1 null neurons (Santos et al., 2017), and all showed normal in vitro morphology, total dendritic length, and synapse density (Fig

[DOI] [PubMed] [Google Scholar] Kaneto H, Katakami N, Kawamori D, Miyatsuka T, Sakamoto K, Matsuoka TA, Matsuhisa M, Yamasaki Y

However, some laboratory studies suggest lithium might increase protein aggregation in certain neurodegenerative contexts or cause mitochondrial degradation through autophagy

doi: 10.1159/000149799

This method assumes that similar molecules have similar MS fragmentation patterns, meaning that they tend to group closely together in a network, and is able to detect the spectral sets of related molecules (Hollywood et al., 2018)