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The Connection Between Blood Sugar, Energy, and Semaglutide Fatigue There are a few reasons why you might feel tired when taking Ozempic (semaglutide), Wegovy (semaglutide), or compounded semaglutide: Adjustment Phase: When you start a new medication, your body needs time to get used to it, which may contribute to initial feelings of fatigue

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Theyre short chains of amino acids (the same building blocks that make up proteins) that carry targeted instructions