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Most scholars recommend oral budesonide as an alternative first-line therapy for mild to moderate UC, due to its strong and effective anti-inflammatory effect and high safety, Patients with mild to moderate UC may benefit from it, as well as it has fewer adverse reactions and side effects than general glucocorticoids (53)

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It has also been shown to influence lipid metabolism enzyme activity, including hormone-sensitive lipase and lipoprotein lipase, and to modulate adipogenic transcription factor expression in adipocyte differentiation models