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Additionally, compared with wild-type cells, PIK3CA mutant colorectal cancer (CRC) cells exhibit elevated anaplerotic -KG production and ATP generation from glutamine

Fahmy, G

Corsini EM, Wang J, Wu CC, Fujimoto J, Negrao MV, Chen R, Quek K, Mitchell KG, Chow CB, Little L, Gumbs C, Song X, Behrens C, Correa AM, Antonoff MB, Swisher SG , Heymach JV, Zhang J, Wistuba II, Futreal PA, Sepesi B, Zhang J