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employed lentiviral transduction of four human genes (hOCT4, hSOX2, hKLF4, and hc-MYC) commonly used for iPSC generation in mice and humans [83]

Dysfunctional or uncontrolled inflammation can be characterised as a chronic low-grade inflammation such as that observed in diabetes, obesity and atherosclerosis ( Reference Lloyd-Jones, Adams and Carnethon 1 , Reference Boosalis 2 )

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G6PD and 6PGD are the two enzymes in the PPP which catalyze the reactions to produce NADPH

[PubMed] [Google Scholar] 249.Fernandez-Flores A., Nguyen T., Cassarino D.S

However, it remains to be understood whether and to what extent conduit repair can improve regeneration accuracy and how it correlates with functional recovery