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GO analysis showed that caffeine was involved in the biological processes of inflammation (neutrophil migration, regulation of MAP kinase activity, immune system process, natural killer cell degranulation, etc.), metabolism (response to lipid, glycosphingolipid metabolic process, lipid storage, etc.), and fibrosis (collagen receptor activity, etc.) (Figures 7E,G)

Drugs: Penicillin (Blue et al 1987) and trimethroprim-sulfur (Thomas and Livesey 1998) have been associated with a drug-induced hemolytic anemia in horses

PCAC will make recommendations to the FDA, which will consider the committees advice as well as public comments before making a final decision

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