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Dose-dependent inhibition of mitochondrial ATP synthase by 17 beta-estradiol

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4.5 Induction of tumor cell DNA mutation by polyketide-non-ribosomal peptide synthase operon (pks + ) E

Excess bile, a heme byproduct, can form gallstones, block bile flow, damage the liver and bile ducts, and raise GGT and ROS levels

10.1016/S0161-6420(98)95019-9