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More Info Physical Appearance Stability Solubility Amino Acid Sequence Background Delta Sleep-Inducing Peptide (DSIP), also known as Sleep-Promoting Peptide, is a neuropeptide that has been the subject of extensive research due to its potential role in sleep regulation, stress response, and neuroprotection

Science 359 , 11511156 (2018)

Serial applications of oligomycin (ATP synthase inhibitor, 1 M), FCCP (protonophore, 0.5 M), and rotenone and antimycin A (respiratory complex I and III inhibitor, respectively, 0.5 M) over time enabled calculation of various parameters of mitochondrial respiration in both cell lines

For example, the interaction between ApoE and TREM2, another major risk factor for sporadic AD, has been reported to facilitate the uptake of A by microglia, and AD-linked mutations in TREM2 impair the binding affinity of TREM2 for ApoE leading to A accumulation in the brain (Yeh et al., 2016)

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No correction is done for multiple testing to investigate differences in performance across subgroups