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Electrophysiology studies Current recordings were measured using two-electrode voltage clamp electrophysiology with an AxoClamp 900A microelectrode amplifier (Axon Instruments) and a PowerLab 4/26 chart recorder (ADInstruments) interfaced with LabChart software (version 8) (ADInstruments)

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However, some studies suggest that while LC supplementation raises TMAO levels, it does not necessarily correlate with adverse cardiovascular outcomes in all populations

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