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Tsamis, A., Krawiec, J

For instance, repeated light-dark cycles reduced NK cell cytotoxicity and increased lung tumor burden in rats, while alternating light-dark cycles durations impaired both delayed-type hypersensitivity (DTH) responses and phagocytosis 88,89

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However, this combined approach necessitates careful consideration of critical issues such as drug interactions, additive toxicity, and optimal dosing sequences

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