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(PubMed) Bergman J, Miodownik C, Bersudsky Y, et al

2022;7(40):e202203365

means up-regulation and means down-regulation

In a hospital or clinic, if a medication order allows it, a pharmacist might choose bacteriostatic water to reconstitute a multi-dose vial of a drug so that it can be used for multiple patients/doses (as long as its safe for that drug and patient population)